CBD Oil

cannabidiol

Cannabidiol oils better known as CBD, it is one of more than 100 chemical compounds called cannabinoids that are found in the cannabis plant, Cannabis sativa.

In recent years CBD oils have received a lot of attention with regards to possibly helping with ,many different types of conditions.

General info

CBD oil is made by extracting CBD from the cannabis plant and then diluting it with a carrier oil like coconut oil or hemp seed oil. CBD can be found in a variety of products online and in stores, including dietary supplements, bath soaks, drinks, and food.

It continues to gain momentum in the health and wellness world, with some scientific studies finding that it may ease symptoms of conditions such as chronic pain and anxiety. But more research on CBD has been emerging as it has gained popularity. Still, there are only a few clinical studies on the effects of CBD oil.

Unlike the THC that's in marijuana, CBD oil doesn't get you high. It contains a chemical called cannabidiol that might help relieve stress, anxiety, drug withdrawals, and nerve pain.

However, CBD oil might change the way your body breaks down certain medications. This could make the drugs have a stronger or weaker effect, which can be dangerous. Talk to your doctor before you use CBD oil, especially if you take any medicine or have liver disease.

As a side note CBD oil has been heralded by many as a cure all and modern Panacea (universal remedy) with so many people pushing it so please be careful and don't fall for all the marketing hype. It could prove to be a wonderful substance for a multitude of issues but further research needs be carried out so proceed with caution and don't get your hopes up.

is it psychoactive?

Tetrahydrocannabinol (THC) is what's responsible for the psychoactive effects of cannabis—in other words, what makes you feel "high." CBD oil generally doesn't have THC, although trace amounts might be in products sold in certain oils.

is it legal?

Some cannabis-based products are legal both in the UK, and abroad but you should 'check the laws of the land your in.' We should point out many Cannabidiol products are available to buy legally as food supplements from health stores. But there's no guarantee these are of good quality or provide any health benefits, and the strength and quality varies widely.

Some cannabis-based products are available on prescription as medicinal cannabis. These are only likely to benefit a very small number of patients so please speak to your doctor.

The great debate about whether cannabis should be legalised for recreational (non-medical) use is still ongoing but many countries are now starting to legalise. In the United States it would appear cannabis is legal to use in some states but not others.

warnings

Clinical research has shown that CBD oil can trigger side effects. The severity and type can vary from one person to the next by some side effects observed are: Anxiety, Changes in appetite, Changes in mood Diarrhea, Dizziness, Drowsiness, Dry mouth, Nausea, Vomiting.

Possible interactions with medications

Brivaracetam (Briviact):

Brivaracetam is changed and broken down by the body. CBD might decrease how quickly the body breaks down brivaracetam. This might increase levels of brivaracetam in the body.

Caffeine:

Caffeine is changed and broken down by the body. CBD might decrease how quickly the body breaks down caffeine. This might increase levels of caffeine in the body.

Carbamazepine (Tegretol):

Carbamazepine is changed and broken down by the body. CBD might decrease how quickly the body breaks down carbamazepine. This might increase levels of carbamazepine in the body and increase its side effects.

Citalopram (Celexa):

Citalopram is changed and broken down by the body. CBD might decrease how quickly the body breaks down citalopram. This might increase levels of citalopram in the body and increase its side effects.

Clobazam (Onfi):

Clobazam is changed and broken down by the liver. CBD might decrease how quickly the liver breaks down clobazam. This might increase the effects and side effects of clobazam.

Eslicarbazepine (Aptiom):

Eslicarbazepine is changed and broken down by the body. CBD might decrease how quickly the body breaks down eslicarbazepine. This might increase levels of eslicarbazepine in the body by a small amount.

Everolimus (Zostress):

Everolimus is changed and broken down by the body. CBD might decrease how quickly the body breaks down everolimus. This might increase levels of everolimus in the body.

Lithium:

Taking higher doses of CBD might increase levels of lithium. This can increase the risk of lithium toxicity.

Methadone (Dolophine):

Methadone is broken down by the liver. CBD might decrease how quickly the liver breaks down methadone. Taking cannabidiol along with methadone might increase the effects and side effects of methadone.

Rufinamide (Banzel):

Rufinamide is changed and broken down by the body. CBD might decrease how quickly the body breaks down rufinamide. This might increase levels of rufinamide in the body by a small amount.

Sedative medications (CNS depressants):

CBD might cause sleepiness and slowed breathing. Some medications, called sedatives, can also cause sleepiness and slowed breathing. Taking CBD with sedative medications might cause breathing problems and/or too much sleepiness.

Sirolimus (Rapamune):

Sirolimus is changed and broken down by the body. CBD might decrease how quickly the body breaks down sirolimus. This might increase levels of sirolimus in the body.

Stiripentol (Diacomit):

Stiripentol is changed and broken down by the body. CBD might decrease how quickly the body breaks down stiripentol. This might increase levels of stiripentol in the body and increase its side effects.

Tacrolimus (Prograf):

Tacrolimus is changed and broken down by the body. CBD might decrease how quickly the body breaks down tacrolimus. This might increase levels of tacrolimus in the body.

Tamoxifen (Soltamox):

Tamoxifen is changed and broken down by the body. CBD might affect how quickly the body breaks down tamoxifen. This might affect levels of tamoxifen in the body.

Topiramate (Topamax):

Topiramate is changed and broken down by the body. CBD might decrease how quickly the body breaks down topiramate. This might increase levels of topiramate in the body by a small amount.

Valproate:

Valproic acid can cause liver injury. Taking cannabidiol with valproic acid might increase the chance of liver injury. CBD and/or valproic acid might need to be stopped, or the dose might need to be reduced.

Warfarin:

CBD might increase levels of warfarin, which can increase the risk for bleeding. CBD and/or warfarin might need to be stopped, or the dose might need to be reduced.

Zonisamide:

Zonisamide is changed and broken down by the body. CBD might decrease how quickly the body breaks down zonisamide. This might increase levels of zonisamide in the body by a small amount.

Medications changed by the liver (Cytochrome P450 1A1 (CYP1A1) substrates)